This study examined why intensive care unit (ICU) nurses experience difficulties in respecting the wishes of patients in end-of-life care in Japan. A questionnaire survey was conducted with ICU nurses working in Japanese university hospitals. The content of their narratives was analyzed concerning the reasons why the nurses believed that patients' wishes were not respected. The most commonly stated reason was that patients' wishes were impossible to realize, followed by the fact that decision making was performed by others, regardless of (...) whether the patients' wishes were known, if the death was sudden, and time constraints. Many nurses wanted to respect the wishes of dying patients, but they questioned how patients die in ICUs and were therefore faced with ethical dilemmas. However, at the same time, many of the nurses realized that respecting patients' wishes about end-of-life care in an ICU would be difficult and that being unable to respect these wishes would often be unavoidable. The results thus suggest that there has been insufficient discussion about respecting the wishes of patients undergoing intensive care. (shrink)

Previous studies have found that serum lipid levels independently associate with mental health problems in adulthood. However, little is known about the association between serum lipid levels and positive aspects of mental health such as resilience and self-esteem, which develop in adolescence. The aim of this study is to examine the association between serum lipid levels and resilience and self-esteem in Japanese adolescents. Data were pooled data from the Adachi Child Health Impact of Living Difficulty study in 2016 and 2018, (...) a school-based, cross-sectional study in Adachi City, Tokyo, Japan. Resilience of the child was assessed by caregivers, and self-esteem was self-identified via questionnaires. Serum lipid levels [total cholesterol, low-density lipoproteins, and high-density lipoproteins ] were assessed in school health checkup, in addition to height and weight measurements. Multiple linear regression was applied to investigate the association between standardized serum lipid levels and resilience and self-esteem. LDL showed inverse association with resilience [β = −1.26, 95% confidence interval = −2.39 to −0.14] after adjusting for child’s BMI, month of birth, sex, absence of parent, household income, caregiver’s mental health, and lifestyle. We also found an inverse association of total cholesterol and higher LDL cholesterol with self-esteem. HDL cholesterol was not associated with resilience and self-esteem. Among Japanese adolescent, total and LDL cholesterol may be biomarkers of resilience and self-esteem. (shrink)

Child poverty leads to various negative consequences, including low self-esteem, which is a risk factor for mental illness, suicide, or poor academic achievement. However, little is known about why child poverty leads to low self-esteem. We aimed to elucidate the association of child poverty and low self-esteem based on the ecological model, which includes family-level, school-level, and community-level factors. Data were obtained from the Adachi Child Health Impact of Living Difficulty (A-CHILD) study in 2016, and participants included 1,652 children in (...) fourth grade (534 pairs), sixth grade (530 pairs), and eighth grade (588 pairs) living in Adachi City, Tokyo. A questionnaire survey was implemented to assess child poverty, parental mental health, parental involvement with children, parental social capital by caregivers, and self-esteem and school social capital by children. The structural equation model was applied to elucidate the association between child poverty and low self-esteem, using family-level (parental mental health and parental involvement with children), school-level (school social capital), and community-level (parental social capital) factors. Child poverty was associated with low self-esteem. Child poverty leads to poor parental involvement, which can be indirectly associated with poor parental mental health and poor parental social capital, and poor parental involvement was directly or indirectly associated with low self-esteem through poor school social capital. To mitigate the impact of child poverty on low self-esteem, comprehensive health policies targeting family-level (parental mental health and parental involvement with children), school-level (school social capital), and community-level (parental social capital) factors may be effective. (shrink)

By drawing on service encounter data in Japanese, this paper analyzes a previously undocumented request action initiated by a service provider to a client as a necessary step to provide the service. The service provider and their client, both exercising respective deontic rights, collaboratively construct a request turn in particular ways. In this case, due to the Japanese SOV word order, the service provider takes advantage of segmenting their request turn to allow the recipient clients to begin compliance, who thereby (...) acquiesce to the service provider’s deontic authority at the earliest point. By bringing the request turn to completion after the client’s compliance while reflexively showing their deontic and beneficiary stances in the turn final component, the service provider displays commitment to balancing out their relative deontic status to the client. (shrink)

Understanding employee stress has become a key issue for top management for corporate growth and risk reduction. So far, annual employee satisfaction surveys have been conducted to assess the soundness of an organization. However, since it is difficult to collect questionnaires quantitatively and continuously, there is a need for a practical method that can be used to frequently measure group stress levels with a small burden on employees. We propose such a method and evaluated four combinations of approaches, using activity/rest (...) duration distributions from body motion data and generating estimation models on an individual/group basis. The optimal result was obtained when modeling was made on a group basis by using the activity duration distribution, making it possible to assess the degree of the stress of employees quantitatively and easily, and this showed the possibility of this method being useful as a management guide for companies. (shrink)

This paper considers the process of how the image of Mount Sumeru, the axis mundi of the Indian Buddhist cosmology, was transmitted from the Indo-Iranian cultural sphere to the Chinese cultural sphere in the fifth and sixth centuries. The research focus is mainly on the representations of Mt. Sumeru in the wall paintings of two monumental Buddhist sites from this period, the Kizil Grottoes (Kucha) and the Mogao Grottoes (Dunhuang), with reference to a relevant image in the Yungang Grottoes (Datong). (...) As the monks of Kucha were in direct intellectual contact with contemporaneous India via the Sanskrit language, it is a purely Indian Buddhist cosmological worldview that is reflected in early Kizil paintings. In Dunhuang, on the other hand, the earliest-extant Sumeru representation clearly shows the visual syncretism of Buddhist and Taoist cosmologies. These visual symbols of the “World” are composites of multiple historical factors, such as languages, geopolitical situation of regional powers, and ideological trends of the regions. (shrink)

Recently, agent technologies have attracted a lot of interest as an emerging programming paradigm. With such agent technologies, services are provided through collaboration among agents. At the same time, the spread of mobile technologies and communication infrastructures has made it possible to access the network anytime and from anywhere. Using agents and mobile technologies to realize ubiquitous computing systems, we propose a new framework based on KODAMA and VPC. KODAMA provides distributed management mechanisms by using the concept of community and (...) communication infrastructure to deliver messages among agents without agents being aware of the physical network. VPC provides a method of defining peer-to-peer services based on agent communication with policy packages. By merging the characteristics of both KODAMA and VPC functions, we propose a new framework for ubiquitous computing environments. It provides distributed management functions according to the concept of agent communities, agent communications which are abstracted from the physical environment, and agent collaboration with policy packages. Using our new framework, we conducted a large-scale experiment in shopping malls in Nagoya, which sent advertisement e-mails to users' cellular phones according to user location and attributes. The empirical results showed that our new framework worked effectively for sales in shopping malls. (shrink)

The scientific, ethical, and policy issues raised by research involving the engraftment of human neural stem cells into the brains of nonhuman primates are explored by an interdisciplinary working group in this Policy Forum. The authors consider the possibility that this research might alter the cognitive capacities of recipient great apes and monkeys, with potential significance for their moral status.

Stigmatization and sharming of healthcare workers in Japan during the coronavirus 2019 pandemic reveal uniquely Japanese features. Seken, usually translated as ‘social appearance or appearance in the eyes of others,’ is a deep undercurrent woven into the fabric of Japanese life. It has led to providers who become ill with the SARS-CoV-2 virus feeling ashamed, while concealing their conditions from coworkers and public health officials. It also has led to healthcare providers being perceived as polluted and their children being told (...) they were not welcome in schools. Although such experiences are not isolated to Japan and have appeared in other parts of the world, the cultural forces driving them in Japan are unique. Overcoming stigmatization and shaming of Japanese healthcare providers will require concerted efforts to understand cultural barriers and to view such practices as raising human rights issues affecting the safety and well-being of all. (shrink)

We conduct an online survey experiment to determine the influence of multifunctionality recognition in agriculture on the price premiums of environmental-friendly agricultural products. We use the case of fish-friendly rice produced in Shiga prefecture, Japan, which contributes to the conservation of the water and ecosystem in rural areas around Lake Biwa by setting up fish ways and reducing the use of herbicides. We assume two conditions for consumers to pay premiums on environmental-friendly agricultural products. The first is that consumers recognize (...) multifunctionality in agriculture. The second condition is that consumers have a correct understanding of environment-friendly agricultural products. We thus examine the effects of respondents’ attributes on their responses to two types of visual stimuli: one associated with the multifunctionality of agriculture and information about environment-friendly agricultural products. In the analysis of the respondents; willingness to pay, the price premium of the group with both the stimulus and information is significantly higher than the price premium of the control group with no interventions. However, the price premium of the group with only the stimulus is not statistically different for the control group. The policy implication of this research is that consumers are more likely to support agri-environmental policies if they recognize both the multifunctionality of agriculture and the properties of environmental-friendly agricultural products. The two types of stimuli have complimentary effects on increasing price premiums. Promoting the recognition of multifunctionality is especially important for those who do not usually access information on agriculture. (shrink)

November 4th-5th, 2012 at Kyoto University. Organizers: Hisashi Nakao & Pierre-Alain Braillard.

Specificities of enzymes involved in plant specialized metabolism, including flavonoid biosynthesis, are generally promiscuous. This enzyme promiscuity has served as an evolutionary basis for new enzyme functions and metabolic pathways in land plants adapting to environmental challenges. This phenomenon may lead, however, to inefficiency in specialized metabolism and adversely affect metabolite‐mediated plant survival. How plants manage enzyme promiscuity for efficient specialized metabolism is, thus, an open question. Recent studies of flavonoid biosynthesis addressing this issue have revealed a conserved strategy, namely, (...) a homolog of chalcone isomerase with no catalytic activity binds to chalcone synthase, a key flavonoid pathway enzyme, to narrow (or rectify) the enzyme's highly promiscuous product specificity. Reducing promiscuity via specific protein–protein interactions among metabolic enzymes and proteins may be a solution adopted by land plants to achieve efficient operation of specialized metabolism, while the intrinsic promiscuity of enzymes has likely been retained incidentally. (shrink)

We study L∞κ-freeness in the variety of Boolean algebras. It is shown that some of the theorems on L∞κ-free algebras which are known to hold in varieties such as groups, abelian groups etc. are also true for Boolean algebras. But we also investigate properties such as the ccc of L∞κ-free Boolean algebras which have no counterpart in the varieties above.

Previous research suggested a role of gaze in preference formation, not merely as an expression of preference, but also as a causal influence. According to the gaze cascade hypothesis, the longer subjects look at an item, the more likely they are to develop a preference for it. However, to date the connection between viewing and liking has been investigated predominately with self-paced viewing conditions in which the subjects were required to select certain items from simultaneously presented stimuli on the basis (...) of perceived visual attractiveness. Such conditions might promote a default, but non-mandatory connection between viewing and liking. To explore whether the connection is separable, we examined the evaluative processing of single naturalistic food images in a 2 x 2 design, conducted completely within subjects, in which we varied both the type of exposure (self-paced versus time-controlled) and the type of evaluation (non-exclusive versus exclusive). In the self-paced exclusive evaluation, longer viewing was associated with a higher likelihood of a positive evaluation. However, in the self-paced non-exclusive evaluation, the trend reversed such that longer viewing durations were associated with lesser ratings. Furthermore, in the time-controlled tasks, both with non-exclusive and exclusive evaluation, there was no significant relationship between the viewing duration and the evaluation. The overall pattern of results was consistent for viewing times measured in terms of exposure duration (i.e., the duration of stimulus presentation on the screen) and in terms of actual gaze duration (i.e., the amount of time the subject effectively gazed at the stimulus on the screen). The data indicated that viewing does not intrinsically lead to a higher evaluation when evaluating single food images; instead, the relationship between viewing duration and evaluation depends on the type of task. We suggest that self-determination of exposure duration may be a prerequisite for any influence from viewing time on evaluative processing, regardless of whether the influence is facilitative. Moreover, the purported facilitative link between viewing and liking appears to be limited to exclusive evaluation, when only a restricted number of items can be included in a chosen set. (shrink)

Summary Syriac translations and Syriac scholars played an important role in the transmission of the sciences, including the mathematical sciences, from the Greek to the Arabic world. Relatively little, unfortunately, remains of the translations and original mathematical works of earlier Syriac scholars, but some materials have survived, and further glimpses of what once existed may be gained from works of later authors. The paper will provide an overview of the earlier materials that have survived or are known to have existed. (...) This will be followed by an account of some of the later materials, which will include an example illustrating how further earlier materials can be recovered from the writings of later authors, and a mention, by way of an epilogue, of an instance where a Syriac scholar was involved in a major historical and scientific event in the West, namely the reform of the calendar by Gregory XIII. (shrink)

Transcranial direct current stimulation (tDCS) has been recognized as a promising tool for investigating the causal relationship between specific brain areas of interest and behavior. However, the reproducibility of previous tDCS studies is often questioned because of failures in replication. This study focused on the effects of tDCS on one cognitive domain: beauty perception. To date, the modulation of beauty perception by tDCS has been shown in two studies:Cattaneo et al. (2014)andNakamura and Kawabata (2015). Here, we aimed at replicating their (...) studies and investigating the effects of tDCS on beauty perception using the following parameters: (1) cathodal stimulation over the medial prefrontal cortex (mPFC) (Nakamura and Kawabata, 2015); (2) anodal stimulation over the left dorsolateral prefrontal cortex (lDLPFC) (Cattaneo et al., 2014). We also performed a more focal stimulation targeting the orbitofrontal cortex (OFC) to determine the optimal stimulation site for modulating beauty perception (3). Participants rated the subjectively-perceived beauty of the images before and after the tDCS administration. We divided images into four clusters according to the obtained scores in our preliminary study and examined changes in beauty ratings in each image cluster separately to exclude factors, such as stimuli attributions that may reduce tDCS effects. The results showed no strong effects of tDCS with the same parameters as in previous studies on beauty rating scores in any image cluster. Likewise, anodal stimulation over the OFC did not result in a change in rating scores. In contrast to previous studies, the current study did not corroborate the effects of tDCS on beauty perception. Our findings provide evidence regarding the recent reproducibility issue of tDCS effects and suggest the possible inflation of its effects on cognitive domains. (shrink)

BackgroundA brief measure of dispositional mindfulness is important for applied research on mindfulness. Although short forms of the Five Facet Mindfulness Questionnaire, which measures the five aspects of mindfulness, have been developed worldwide, the validity and reliability of the Japanese version has not been examined. This study aims to examine the validity and reliability of the 24-item and 15-item versions of the FFMQ in Japan, which are the most widely used versions worldwide.MethodsOnline surveys were conducted for 889 adults in Japan (...) through an online survey company using self-reported questionnaires including the FFMQ to confirm the factor structure and validity. To examine construct validity, we examined the relationship between the short form of FFMQ and mind wandering, interoceptive awareness, experiential avoidance, cognitive fusion, openness, neuroticism, self-compassion, depression, and anxiety, which have been theoretically or empirically shown to be related to mindfulness. In addition, 137 adults responded to the FFMQ again, after four weeks, for the test-retest reliability.ResultsThe correlated five-factor and four-factor models and the higher-order factor hierarchical model did not show sufficient goodness of fit, while the 24-item version showed acceptable fit when uncorrelated method factors loaded on by the positive and negative items were added. However, the 15-item version did not show acceptable fits for any of the models. Regarding reliability, the 24-item version showed acceptable values. In terms of the relationship between the original and the shortened version of the FFMQ, the 24-item version shared approximately 80% of the variance with the original one. In addition, although the wording effects of positive and negative items seemed to affect the correlations between the FFMQ and the other scales, the associations with related concepts were as predicted generally, supporting the construct validity of the short form of the FFMQ.ConclusionIn Japan, the 24-item version of FFMQ showed acceptable validity and reliability similar to the original version, and we recommend that the 24-item version be used. (shrink)

Background: In sports psychology research, the Stroop test and its derivations are commonly used to investigate the benefits of exercise on cognitive function. The measures of the Stroop test and the computed interference often have different interclass correlation coefficients. However, the ICC is never reported in cross-over designs involving multiple variances associated with individual differences.Objective: We investigated the ICC of the Stroop neutral and incongruent tests and interference, and reverse Stroop task using the linear mixed model.Methods: Forty-eight young adults participated (...) in a cross-over design experiment composed of 2 factors: exercise mode and time. Before and after each intervention, participants completed the Stroop neutral and incongruent, and the reverse-Stroop neutral and incongruent tests. We analyzed for each test performance and interference and calculated ICC using the linear mixed model.Results: The linear mixed model found a significant interaction of exercise mode and time for both the Stroop and reverse-Stroop tasks, suggesting that exercise mode influences the effect of acute exercise on inhibitory function. On the other hand, there was no significant effect of exercise mode for both the Stroop and reverse-Stroop interference. The results also revealed that calculating both the Stroop and reverse-Stroop interference resulted in smaller ICCs than the ICCs of the neutral and incongruent tests for both the Stroop and reverse-Stroop tasks.Conclusion: The Stroop and reverse-Stroop interferences are known as valid measures of the inhibitory function for cross-sectional research design. However, to understand the benefits of acute exercise on inhibitory function comprehensively by cross-over design, comparing the incongruent test with the neutral test also seems superior because these tests have high reliability and statistical power. (shrink)

We investigated whether the inferior parietal lobule (IPL) responds in real-time to multisensory inconsistency during movement. The IPL is thought to be involved in both the detection of inconsistencies in multisensory information obtained during movement and that obtained during self-other discrimination. However, because of the limited temporal resolution of conventional neuroimaging techniques, it is difficult to distinguish IPL activity during movement from that during self-other discrimination. We simultaneously conducted electroencephalography (EEG) and near-infrared spectroscopy (NIRS) with the goal of examining IPL (...) activity with a high spatiotemporal resolution during single reaching movements. Under a visual feedback-delay condition, gamma event-related synchronization (γ-ERS), i.e., an increase in gamma (31–47 Hz) EEG power, occurred during reaching movements. This γ-ERS is considered to reflect processing of information about prediction errors. To integrate this temporal information with spatial information from the NIRS signals, we developed a new analysis technique that enabled estimation of the regions that show a hemodynamic response characterized by EEG fluctuation present in the visual feedback-delay condition. As a result, IPL activity was explained by γ-ERS specific to visual feedback delay during movements. Thus, we succeeded in demonstrating real-time activation of the IPL in response to multisensory inconsistency. However, we did not find any correlation between either IPL activity or γ-ERS with the sense of agency. Therefore, our results suggest that while the IPL is influenced by prediction error signals, it does not engage in direct processing underlying the conscious experience of making a movement, which is the foundation of self-other discrimination. (shrink)

The sophisticated function of the central nervous system (CNS) is largely supported by proper interactions between neural cells and blood vessels. Accumulating evidence has demonstrated that neurons and glial cells support the formation of blood vessels, which in turn, act as migratory scaffolds for these cell types. Neural progenitors are also involved in the regulation of blood vessel formation. This mutual interaction between neural cells and blood vessels is elegantly controlled by several chemokines, growth factors, extracellular matrix, and adhesion molecules (...) such as integrins. Recent research has revealed that newly migrating cell types along blood vessels repel other preexisting migrating cell types, causing them to detach from the blood vessels. In this review, we discuss vascular formation and cell migration, particularly during development. Moreover, we discuss how the crosstalk between blood vessels and neurons and glial cells could be related to neurodevelopmental disorders. (shrink)

We agree that motivation to share emotions and other mental states is crucial for communicative development, but human infants are highly selective in sharing mental states, and this is well taken evolutionarily. Young chimpanzees may also have motivation to imitate mothers. Thus, uniquely human cognition and culture may not be reduced to a few basic abilities and/or inclinations.

This paper considers the process of how the image of Mount Sumeru, the axis mundi of the Indian Buddhist cosmology, was transmitted from the Indo-Iranian cultural sphere to the Chinese cultural sphere in the fifth and sixth centuries. The research focus is mainly on the representations of Mt. Sumeru in the wall paintings of two monumental Buddhist sites from this period, the Kizil Grottoes (Kucha) and the Mogao Grottoes (Dunhuang), with reference to a relevant image in the Yungang Grottoes (Datong). (...) As the monks of Kucha were in direct intellectual contact with contemporaneous India via the Sanskrit language, it is a purely Indian Buddhist cosmological worldview that is reflected in early Kizil paintings. In Dunhuang, on the other hand, the earliest-extant Sumeru representation clearly shows the visual syncretism of Buddhist and Taoist cosmologies. These visual symbols of the “World” are composites of multiple historical factors, such as languages, geopolitical situation of regional powers, and ideological trends of the regions. (shrink)

Iron Eyes: The Life and Teachings of Obaku Zen Master Tetsugen Doko, Helen J. Baroni, pp. ix+259, ISBN 0-7914-6892-5.